Data-Source Provenance

Last updated: 2026-07-09 · Generated from the canonical source hierarchy

ALETHEIA's chemical-safety data is cited, not scraped. Every hazard classification, regulatory listing, and exposure figure is attributed to the public authority that issued it. This page lists those authorities. It answers “who our data comes from” — which is distinct from “who we engage with”; for the latter, see the engagement registry and agency directory.

184 agency references · 57 issuing organizations · 95 cited domains · 23 listing programs.

Not listed ≠ safe. If a substance is not listed by an authority below, that means the authority has not assessed or has not restricted it — not that it is known to be safe. Absence of a listing is absence of assessment, not a clearance.

How determinations reach us. Some determinations are surfaced through public-domain aggregators. For example, IARC carcinogen classifications are surfaced via the U.S. EPA CompTox Chemicals Dashboard's public-domain aggregation and cited to the underlying IARC monograph. Where a source is in the public domain (U.S. federal and state) we cite it as a provenance and trust feature; where reuse is conditioned on attribution (EU and other open-data bodies) we attribute the issuing authority.

United States — federal

Public-domain determinations from U.S. federal agencies.

US EPA Public domainChemical hazard, tox, and exposure data — including EPA CompTox/DSSTox aggregations (which also surface other authorities' public determinations).
US FDA Public domainFood, drug, and cosmetic safety determinations.
US NTP / NIEHS Public domainReport on Carcinogens listings.
US NIOSH Public domainRecommended exposure limits.
US OSHA Public domainPermissible exposure limits.
US DEA Public domainControlled-substance scheduling.
US CPSC Public domainConsumer-product safety rules.
US CDC / ATSDR Public domainToxicological profiles and NHANES biomonitoring.
US DOT / PHMSA Public domainHazardous-materials transport.
US federal (unspecified) Public domainCited safety determinations.
US USDA Public domainPesticide Data Program residues.
US NRC Public domainCited safety determinations.
US USGS Public domainEnvironmental and geochemical data.
US DHS Public domainCited safety determinations.
US DOE Public domainCited safety determinations.
US DoD Public domainCited safety determinations.

United States — California

State public-record determinations (including Proposition 65).

California OEHHA (Prop 65) Public domainCalifornia Proposition 65 listings and cancer/reproductive-toxicity determinations.
US state agencies (other) Public domainCited safety determinations.
California CARB Public domainCited safety determinations.
California DTSC Public domainCited safety determinations.

European Union & EU bodies

EU open-data determinations, attributed to the issuing body.

European Commission Open data · attributedEU regulations and directives.
EU ECHA Open data · attributedREACH registrations, CLP classifications, SVHC candidate list.
EU Cosmetics Regulation / CosIng Open data · attributedEU Cosmetics Regulation annexes and the CosIng inventory.
EU EFSA Open data · attributedOpenFoodTox food-safety assessments.
EMA (European Medicines Agency) Open data · attributedCited safety determinations.
EU SCCS Open data · attributedScientific opinions on cosmetic-ingredient safety.
Council of Europe Open data · attributedCited safety determinations.

Other national authorities

National chemical-safety authorities we cite, attributed to each.

Health Canada Open data · attributedDomestic Substances List and Chemicals Management Plan.
Japan (METI / MHLW / NITE / MAFF) Open data · attributedChemical risk and GHS classifications.
Australia (AICIS / APVMA / FSANZ) Open data · attributedIndustrial-chemical, pesticide, and food-standards determinations.
UK Government / MHRA Open data · attributedChemical and medicines regulation.
France (ANSES) Open data · attributedFood, environmental, and occupational health assessments.
Germany (BfR / UBA / BfArM) Open data · attributedRisk assessments (BfR / UBA).
China (MEE) Open data · attributedChemical inventory and controls.
Denmark (MST / EPA) Open data · attributedEnvironmental and chemical determinations.
Brazil ANVISA Open data · attributedCited safety determinations.
India Open data · attributedCited safety determinations.
Korea (NIER, K-REACH) Open data · attributedChemical registration (K-REACH).
Russia Open data · attributedCited safety determinations.

United Nations & intergovernmental

Treaty bodies and international scientific authorities.

WHO / IPCS Open data · attributedInternational health assessments and IPCS INCHEM monographs.
UN treaty secretariats Open data · attributedMultilateral chemical treaty listings (POPs, PIC, mercury, ozone).
UN GHS Open data · attributedGlobally Harmonized System of classification and labelling.
UN / UNEP Open data · attributedInternational environmental programmes.
Codex Alimentarius / JECFA (FAO-WHO) Open data · attributedFood-additive and contaminant evaluations.
IMO Open data · attributedCited safety determinations.
OECD Open data · attributedHarmonized test methods and assessments.
IAEA Open data · attributedRadiological safety guidance.
ILO Open data · attributedCited safety determinations.

Scientific & industry authorities we cite

Specialist scientific and standards authorities whose determinations we cite and attribute.

IARC / WHOCarcinogen classifications — surfaced via EPA CompTox's public-domain aggregation and cited to the IARC monograph.
IFRAFragrance-ingredient use standards.
ASHRAE (Standard 34) / refrigerant safety standardsRefrigerant safety-group classifications.
NGO / advocacy & professional bodies Open data · attributedAdditional cited scientific and professional references.
ACGIHThreshold Limit Values (occupational).
NSF International Open data · attributedProduct-standard certifications.
CIR (Cosmetic Ingredient Review)Cosmetic-ingredient safety reviews.
ICRPRadiological protection guidance.
ISOInternational standards.

Sources we are evaluating

Established chemical-safety and toxicology data sources we do not yet ingest — each is a candidate we verify for machine access and licence before use.

ASEAN Cosmetic Directive annexes · China IECSC (MEE) · DFG MAK (Germany) · ECHA RAC opinions / SVHC candidate list (deeper) · ECHA eChemPortal (OECD gateway) · EU CLP Annex VI full table · EU Pesticides Database · EU RAC / SCOEL OELs · GESTIS Substance Database (DGUV, Germany) · Health Canada Cosmetic Ingredient Hotlist · IPCS INCHEM (WHO — CICADs/EHCs) · Korea KECI / K-REACH (NIER) · NLM HSDB / ChemIDplus (legacy TOXNET) · OECD QSAR Toolbox · Open Beauty Facts (ODbL) · Philippines PICCS · Switzerland FOEN · Taiwan TCSCA · Turkey KKDIK · US EPA ECOTOX · US EPA TRI / ChemView · US FDA GRAS / SCOGS

Standing disclaimers

Evidence syntheses, not peer-reviewed publications. Holistic Quality LLC publishes AI-assisted, human-verified evidence syntheses of the published scientific literature. They are working documents — not peer-reviewed journal publications — and reflect our synthesis and analysis; they are not a statement of fact about any named person, company, or institution except where a primary source is cited and linked.

Not professional advice. Informational content only — not medical, legal, financial, or regulatory advice. Nothing here diagnoses, treats, or predicts individual outcomes. Verify information against the cited sources before relying on it for safety-critical decisions.

Sourcing. Statistics and scientific claims are attributed to cited sources; each research artifact carries a full reference list and a plain statement of how it was produced. Associations described are not assertions of causation unless a cited source establishes it.

Commercial transparency. Holistic Quality LLC operates commercial services in the same ecosystem (including the ALETHEIA safety API). Research artifacts are self-funded; no external sponsor, advertiser, or payer influences findings.